Core Facility – µFlu Microfabrication and Microfluidics Core Facility

Microfluidics is an emerging field with applications across a wide range of scientific disciplines—from studying flow dynamics and generating synthetic cells using droplet-based systems to continuous flow setups and complex organ-on-a-chip models.
The newly established Microfluidic Core Facility (µFlu CF) at the Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM), Heidelberg University, is dedicated to making this versatile technology accessible to all interested research groups in and around the Neuenheimer Feld.

Project Request

Timeline of a Project Request at the Microfluidics Core Facility. The steps are: First Contact, Research Plan, Chip Design & Fabrication, Training & Introduction, Lab Work and Data Acquisition & Analysis

To start a collaboration with the Core Facility, simply write an email to Dr. Sadaf Pashapour, with a short description of the project. 

E-Mail: microfluidics@imseam.uni-heidelberg.de

Services & Equipment

In our µFlu CF, we will support researchers from the start by giving input to the project design, to the production of microfluidic chips up to conducting the experiments in our S1 and S2 Biosafety laboratories.
Additionally, we are offering an introduction to the microfluidic work flow, which includes the handling and usage of the microfluidic chips. These tasks can be fulfilled at the facility either independently or under supervision.
We have several instruments in our facility, which are used by the staff to fabricate microfluidic devices ranging from 5µm up to 3mm with different techniques. Hereby, we are not only concentrating on the generation of PDMS-based microfluidic chips, but also on the application of nested glass capillary-based devices or 3D printed devices and structures.

Services

  • Droplet-based microfluidics
  • Microfabrication of devices for cell migration
  • Real-time deformation cytometry
  • Organ-on-chip techniques (under development)

Continuous Flow Experiments:

  • On-chip particle sorting
  • Gradient-on-chip
  • Lipidnanoparticles (LNPs)

Further Information on our Services

Equipment

Microfluidics-Chip Production and Validation Equipment:

  • Mask-less Aligner
  • Interference Profilometer
  • High precision 3D printer

Microfluidics Equipment:

  • Microfluidic Station
  • Micropipettepuller and Microforge
  • Oxygen Plasma

Further Information on our Equipment

Contact

Dr. Sadaf Pashapour 
Head of the Microfluidics Core Facility

E-Mail: microfluidics@imseam.uni-heidelberg.de
Phone: +49 6221 54 15726

Institute for Molecular Systems Engineering and Advanced Materials
Im Neuenheimer Feld 225
69120 Heidelberg

Office: 03.361
Lab: 03.363

Portrait of a smiling woman

Selected publications

Table

Walther T, Emmert M, Platzmann I, Pashapour S, Göpfrich K. (2025) “A DNA hydrogel-based microparticle platform for the bottom-up assembly of artificial cells and tissues” - In Preparation

Funding Resources

Images of the Institutions funding the Microfluidics CF. These are the Health + Life Science Alliance Heidelberg Mannheim and SPP2451